ATOPALM's Technology for trouble free skin.

Recreation of the lamellar structure of skin lipids


MLE is original technology from NeoPharm that flawlessly mimics the lamellar structure of the natural skin lipids and provides the ultimate in revitalizing the skin's moisture through the restoration of the protective barrier system. Ideal for dry and sensitive skin. The special cross pattern of the MLE shows that it is identical to the lipid lamellar structure of the skin. This provides a new standard for dermatological science.

MLE is mild and skin friendly because the structure of plant derived ceramides,fatty acids and cholesterol is identical to that of the lipid lamellar structure of the skin. The restoration of the skins' protective moisture barrier system enables it to successfully lock in moisture and help protect the skin from environmental stresses. It is rich, non-greasy, not sticky and quickly absorbed. It soothes and calms agitated skin and softens and smooths dry, rough skin.

MLE Care system

Authentication of MLE Technology

  • Patents: Domestic patent registered (KR 1999-0003541),the U.S. patent technology applied (no. US6221371), and Japanese patent technology applied (no. JP38871828)
  • Clinical tests completed by Yonsei University Medical School and Chungnam University Medical School
  • Published research articles in many renowned journals including the Journal of Investigative Dermatology (JID) and the Korean Journal of Investigative Dermatology

Clinical Effects of MLE

A clinical test in Yonsei University

A clinical test in Chungnam University

ATOPALM Science - Global Technology Approval

  • OCT 2003
    "Effects and features of the MLE formulation" in the Journal of Investigative Dermatology
  • FEB 2003
    "Clinical results of the MLE an atopy dermatitis" at the International Society of Dermatology in Russia 
  • JUL 2002
    "Clinical results of ATOPALM" at the World Congress of Dermatology in France Society for Investigative Dermatology
  • MAY 2002
    "Skin barriers and the lamella structures" at the Society for Investigative Dermatology
  • JUN 2001
    Presented clinical results at the C & T Society for Investigative Dermatology

ATOPALM Science - Global Technology Approval

  • FEB 2006
    "Functions and efforts of a moisturizer as an adjunctive therapy" in the Journal of Skin Barrier Research
    patented in China
  • APR 2005
    patented in China
  • APR 2005
    patented in Korea
  • OCT 2002
    Passed Safety tests administered by RCH, an FDA accredited institution
  • APR 2001
    patented in the United States
  • 1999
    ATOPALM's ceramide and MLE formulation technology won the KT (Korean ExcellentTechnology).

MLE Before and After

MLE Video Gallery